山东中医杂志2017，Vol.36Issue(10)：860-862,866,4.
疏肝健脾益肾方治疗慢性疲劳综合征临床研究
Clinical Study of Shugan Jianpi Yishen Formula treating Chronic Fatigue Syndrome
郑浪花 1麦杰 1刘映霞1
作者信息
- 1. 广东省深圳市福田区中医院治未病科,广东 深圳 518000
- 折叠
摘要
Abstract
Objective:To explore the clinical efficacy of Shugan Jianpi Yishen formula on chronic fatigue syndrome(CFS). Methods:There were 90 patients with CFS divided into 2 groups according to the digital random table method,45 cases in each group. The control group were given paroxetine hydrochloride (one time a day,20 mg every time);the treatment group were given Shugan Jianpi Yishen formula orally besides the treatment in the control group. The two groups were treated for 8 weeks. The main symptoms of memory loss,insomnia,depression,nervous anxiety score and FS-14 fatigue rating scale before and after treatment of the two groups were compared,serum interleukin-6 (IL-6),tumor necrosis factor-α(TNF-α),interferon-γ(IFN-γ) level before and after treatment of the two groups were compared ,and the total effective rate was compared. Results:The main symptoms of memory loss,insomnia,depression,nervous anxiety scores and FS-14 rating scale after treatment in the treatment group were lower than those in the control group (P<0.01),the level of serum IL-6,TNF-α and IFN-γ were lower than those in the control group(P<0.01),and the total effective rate was higher than that of the control group(P<0.05),with statistical difference. Conclusion:In the treatment of CFS,Shugan Jianpi Yishen formula in combination with western medicine can effectively relieve the clini-cal symptoms and the level of fatigue,and improve the clinical curative effect. The mechanism may be ad-justing the ganglion levels of cytokines.关键词
慢性疲劳综合征/中药治疗/疏肝健脾益肾方Key words
chronic fatigue syndrome/traditional Chinese medicine treatment/Shugan Jianpi Yishen formula分类
医药卫生引用本文复制引用
郑浪花,麦杰,刘映霞..疏肝健脾益肾方治疗慢性疲劳综合征临床研究[J].山东中医杂志,2017,36(10):860-862,866,4.
