中国组织工程研究2017，Vol.21Issue(27)：4300-4305,6.DOI:10.3969/j.issn.2095-4344.2017.27.007
零切迹椎间融合器植入治疗多节段脊髓型颈椎病
Zero-profile interboby fixation system for multi-level cervical spondylotic myelopathy
摘要
Abstract
BACKGROUND: Anterior cervical decompression and fusion has been widely used in the treatment of multi-level cervical spondylotic myelopathy, but accompanied with lots of complications.OBJECTIVE: To investigate the efficacy of zero-profile interboby fixation system for multi-level cervical spondylotic myelopathy.METHODS: Seventy-one patients with multi-level cervical spondylotic myelopathy were randomly divided into two groups, and the patients in group A accepted zero-profile interboby fixation system, and group B accepted cage interboby fixation system. The Japanese Orthopaedic Association score, fusion rate, as well as the incidence of dysphagia and esophageal fistula were detected to compare the efficacy between two groups.RESULTS AND CONCLUSION: (1) All cases were followed-up for 3-34 months, average of 17.5 months. The excellent and good rate at the last follow-up showed no significant difference between two groups. (2) The final fusion rate did not differ significantly between two groups, but the fusion rate in the group A was significantly higher than that in the group B at 6 and 9 months postoperatively (P < 0.05). (3) There was one patient with mild dysphagia in the group A (3％), three mild, five medium, and two severe dysphagia in the group B (29％), which showed significant difference between two groups (P < 0.05). No internal fixation loosening occurred in the group A, but three cases in the group B. The blood loss, operation time and radiology times in the group A were significantly lower than those in the group B (P < 0.05). (4) These results suggest that the effect of these two surgical methods in promoting functional recovery of spinal cord and final fusion rate show no significant differences; however, the zero-profile interboby fixation system exhibits better postoperative stability and interim fusion rate, with lower incidence of dysphagia.关键词
骨科植入物/脊柱植入物/零切迹/融合/脊髓型颈椎病/钛板:吞咽困难:食管漏:颈椎/JOA评分分类
医药卫生引用本文复制引用
王经宇,董玉珍,孙晓辉,崔明星,李清江..零切迹椎间融合器植入治疗多节段脊髓型颈椎病[J].中国组织工程研究,2017,21(27):4300-4305,6.基金项目
河南省医学科技攻关计划项目(201403141)the Key Medical Technologies Research and Development Program of Henan Province in 2014, No. 201403141 （201403141）
