中国畜牧杂志2017，Vol.53Issue(9)：4-7,4.DOI:10.19556/j.0258-7033.2017-09-004
褪黑素对卵母细胞成熟和胚胎体外发育影响的研究进展
Advances in Effects of Melatonin on the Development of Oocytes and Embryos in vitro
摘要
Abstract
Oxidative stress is often involved in culturing oocytes and embryos in vitro due to a relatively high oxygen environment and inadequate antioxidant defenses.Then large amount of reactive oxygen species (ROS) are accumulated and the rate of oocyte and embryo development in vitro was decreased.As an effective antioxidant and free radical scavenger,melatonin can significantly decrease the intracellular ROS level,remove the intracellular free radicals,and improve the in vitro maturation and in vitro development of oocytes.This review focuses on the effects of melatonin on oocyte maturation,embryo in vitro development,embryo quality and its mechanism in order to further enhance the understanding of melatonin in oocyte and fetal development,and lay the foundation for the application of melatonin in the production of embryos in vitro.关键词
卵母细胞/胚胎/褪黑素/抗氧化剂/体外发育Key words
Oocytes/Embryo/Melatonin/Antioxidants/In vitro Development分类
农业科技引用本文复制引用
魏巧莉,房晓欢,曹慧,李俊杰..褪黑素对卵母细胞成熟和胚胎体外发育影响的研究进展[J].中国畜牧杂志,2017,53(9):4-7,4.基金项目
河北省科技计划(17226613D) （17226613D）
河北省高等学校科学技术研究项目(ZD2014002) （ZD2014002）
河北省自然科学基金(C2014204119) （C2014204119）
