北华大学学报（自然科学版）2017，Vol.18Issue(5)：655-658,4.DOI:10.11713/j.issn.1009-4822.2017.05.022
182例真菌感染性角膜炎 临床特征及致病菌分布特征分析
Clinical Features and Distribution of Pathogens in 182 Patients with Fungal Keratitis
摘要
Abstract
Objective To investigate the pathogenesis,population characteristics and distribution of pathogens in patients with fungal keratitis. Method A retrospective analysis was made on clinical data from 182 cases of 182 eyes with fungal keratitis, including their pathogenesis, population characteristics and clinical features. Results Among 182 cases of fungal keratitis,119 patients (119 eyes) treated with 5% natamycin eye drops were cured and the other 31 patients (31 eyes) were improved;31 patients (31 eyes) of 36 patients (36 eyes) treated with 5% natamycin eye drops in combination of voriconazole turned better significantly and 5 patients (5 eyes) of them continued to become worse,and finally 3 patients (3 eyes) of the worse patients were treated with penetrating keratoplasty and 2 patients (2 eyes) of them with evisceration of the eye. Conclusion The most pathogenic bacterium of fungal keratitis was fusarium species. The combination of 5% natamycin with voriconazole can effectively treat fungal keratitis, which may reduce the operability of patients with fungal keratitis.关键词
真菌感染/角膜炎/镰刀菌属/回顾性研究Key words
fungal infection/keratitis/fusarium species/retrospective study分类
医药卫生引用本文复制引用
陈基黎..182例真菌感染性角膜炎 临床特征及致病菌分布特征分析[J].北华大学学报（自然科学版）,2017,18(5):655-658,4.基金项目
江苏省第四期"333工程"项目(2015Z015131). （2015Z015131）
