北京中医药大学学报2017，Vol.40Issue(7)：585-592,8.DOI:10.3969/j.issn.1006-2157.2017.07.010
基于数据挖掘的国医大师颜正华含龙骨处方用药规律研究
Medication rules of formulas containing Longgu (Os Draconis, Bone Fossil of Big Mammals) by national TCM master-YAN Zhenghua based on data mining
摘要
Abstract
Objective To discuss the medication rules of formulas containing Longgu (Os Draconis,Bone Fossil of Big Mammals) by national TCM master-YAN Zhcnghua.Methods On the base of collecting the formulas containing Longgu used by YAN Zhenghua and a database was established based on Traditional Chinese Medicine Inheritance Support System (TCMISS).Apriori algorithm and other data mining methods were built in the data analysis module in TCMISS,and then the module was used for analyzing frequency of single medicinal,frequency of medicinal combinations,association rules and core medicinal combinations.Results The formulas containing Longgu were commonly used for treating insomnia,vertigo and stomachache.The medicinal with high frequency included Muli (Concha Ostreae,Oyster Shell),fried Suanzaoren (Semen Ziziphi Spinosae,Spine Date Seed),Shouwuteng (Caulis Polygoni Multiflori,fleeceflower stem),Danshen (Radix Salviae Mihiorrhizae,Salvia Root) and Chishao (Radix Paeoniae Rubra,Red Peony Root).The medicinal combinations with high frequency included Muli + Longgu,Muli+ fried Suanzaoren,and Longu + fried Suanzaoren.The association rules with support degree ≥ 35 ％ and confidence coefficient ≥ 0.98 included Longgu→Muli,Fuling (Poria,Indian Bread,Poria),Longgu → Muli,Muli,Fuling → Longgu,and Longgu,fried Suanzaoren → Muli.Conclusion The medicinal,used by YAN Zhenghua,mostly have the effects of tranquilizing mind and activating blood,and his formula constructing laws are clear and precise.关键词
龙骨/数据挖掘/关联规则Key words
Longgu (Os Draconis, Bone Fossil of Big Mammals)/data mining/association rules分类
医药卫生引用本文复制引用
吴嘉瑞,郭位先,刘鑫馗,蔺梦娟,王凯欢,张晓朦,杨冰,张冰..基于数据挖掘的国医大师颜正华含龙骨处方用药规律研究[J].北京中医药大学学报,2017,40(7):585-592,8.基金项目
国家自然科学基金资助项目(No.81473547,No.81673829)National Natural Science Foundation of China (No.81473547,No.81673829) （No.81473547,No.81673829）
