北京中医药大学学报2017，Vol.40Issue(7)：607-612,6.DOI:10.3969/j.issn.1006-2157.2017.07.014
冠心病慢性心力衰竭合并高血压患者证候要素和证候分布特点
Distribution characteristics of TCM patterns and pattern factors in patients with coronary heart disease-induced chronic heart failure complicated by hypertension
摘要
Abstract
Objective To compare the influences of hypertension on TCM pattern factors and pattern combinations in patients with coronary heart disease-induced chronic heart failure (CHD-CHF),and provide some reference for pattern differentiation and classification of CHD-CHF.Methods The patients with CHD-CHF (n =252) were chosen from 14 cooperation clinical units through multi-center crosssection study,and then all patients were divided,according to whether they are complicated by hypertension or not,into CHD-CHF + hypertension group and CHD-CHF group.The distribution rules of sex,age,types of heart failure,cardiac grades,pattern factors related to disease nature,pattern factors related to disease locations and pattern combinations were compared between 2 groups for conducting statistical analysis and rules investigation.Results The comparisons in sex,age and heart function had no difference between 2 groups.The pattern factors related to disease nature with the highest occurrence frequency were qi deficiency,blood deficiency and yin deficiency in 2 groups,but occurrence frequency of qi deficiency was lower in CHD-CHF + hypertension group than that in CHD-CHF group (P ＜ 0.01).The pattern factors related to disease locations were heart and meanwhile involved spleen,lung,kidney and liver,and there was no significant difference between 2 groups (P ＞ 0.05).The pattern combinations were almost multi-factor combinations in 2 groups,and 2-factor combination was more in CHD-CHF + hypertension group than that in CHD-CHF group (P ＜ 0.05).The most common pattern types were pattern of qi deficiency and blood stasis,and pattern of dual deficiency of qi and yin with blood stasis in CHD-CHF + hypertension group.Conclusion The percentage of qi deficiency reduces in pattern factors related to disease nature,2-factor combination is more in pattern combinations,and pattern of qi deficiency and blood stasis and pattern of dual deficiency of qi and yin with blood stasis are the most common pattern types in patients with CHD-CHF complicated by hypertension.关键词
慢性心力衰竭/冠心病/高血压/证候要素/证候Key words
chronic heart failure/coronary heart disease/hypertension/pattern factors/patterns分类
医药卫生引用本文复制引用
罗良涛,郭淑贞,张鹏,赵慧辉,王娟,王伟..冠心病慢性心力衰竭合并高血压患者证候要素和证候分布特点[J].北京中医药大学学报,2017,40(7):607-612,6.基金项目
国家中医药管理局中医药行业科研专项资助项目(No.200807007),教育部新世纪优秀人才支持计划(No.NCET-13-0692),北京中医药大学杰出青年人才项目(No.2015-JYB-XYQ002),北京中医药大学创新团队(No.2011-CXTD-06),国家自然科学基金资助项目(No.81470191,No.81503400)Chinese Administration of Traditional Chinese Medicine(No.200807007),New Century Talent Support Program of Ministry of Education(No.NCET-13-0692),National Natural Science Foundation of China(No.81470191,No.81503400) （No.200807007）
