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超声造影时间-强度曲线在肝癌射频消融的应用研究

何雁 李蕾 李小晶 彭红艳 张玲 曾金凤 王丹 沈伶俐

重庆医学2017,Vol.46Issue(26):3649-3650,3654,3.
重庆医学2017,Vol.46Issue(26):3649-3650,3654,3.DOI:10.3969/j.issn.1671-8348.2017.26.017

超声造影时间-强度曲线在肝癌射频消融的应用研究

Application study of contrast-enhanced ultrasound time-intensity curve in hepatocellular carcinoma radiofrequency ablation

何雁 1李蕾 2李小晶 1彭红艳 1张玲 1曾金凤 1王丹 1沈伶俐1

作者信息

  • 1. 武汉大学中南医院超声影像科,武汉430071
  • 2. 武汉科技大学附属天佑医院超声介入科,武汉430064
  • 折叠

摘要

Abstract

Objective To investigate the application value of contrast-enhanced ultrasound(CEUS) time-intensity curve in the radiofrequency ablation treatment of hepatocellular carcinoma.Methods Seventy-six patients with hepatocellular carcinoma (118 tumor lesions) conducted the ultrasound-guided radiofrequency ablation therapy.The acoustic quantitative analysis software was employed to dynamically analyze the residual ablation lesions,which were compared with the examination results of synchronous enhanced MRI,with the pathology as the gold standard,the benign and malignant tumor residual ablation lesions were performed the statistically comparative analysis.Results The accuracy of CEUS effect after liver radiofrequency ablation therapy was 82.2 %,which of enhanced MRI was 83.9 %;the difference between CEUS and enhanced MRI had no statistical significance(P> 0.05),their examination results had higher consistency;the benign residual ablation lesions after radiofrequency ablation had blood perfusion characteristics different from malignant residual lesions,the time-intensity curve showed that IMAX benign residual lesions were smaller than malignant residual lesions(P<0.01).The benign residual lesions of RT and TTP were longer than the malignant residual lesions(P<0.01);diagnosing benign and malignant had no statistical difference between CEUS and enhanced MRI (P>0.05).Conclusion CEUS combined with the time-intensity curve can dynamically,intuitively and quantitatively reflect the blood perfusion differences among inactivated focus,benign and malignant residual lesions,and the surrounding liver parenchyma.

关键词

肝肿瘤/超声检查,多普勒,彩色/导管消融术/射频消融/时间-强度曲线

Key words

liver neoplasms/ultrasonography, doppler, color/catheter ablation/radiofrequency ablation/time-intensity curve

分类

医药卫生

引用本文复制引用

何雁,李蕾,李小晶,彭红艳,张玲,曾金凤,王丹,沈伶俐..超声造影时间-强度曲线在肝癌射频消融的应用研究[J].重庆医学,2017,46(26):3649-3650,3654,3.

重庆医学

1671-8348

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