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埃兹蛋白(Ezrin)在肺癌发生发展中的作用

林忆萍 余和芬

医学分子生物学杂志2017,Vol.14Issue(5):301-305,5.
医学分子生物学杂志2017,Vol.14Issue(5):301-305,5.DOI:10.3870/j.issn.1672-8009.2017.05.000

埃兹蛋白(Ezrin)在肺癌发生发展中的作用

Roles of Ezrin in the Pathogenesis and Progression of Lung Cancer

林忆萍 1余和芬1

作者信息

  • 1. 首都医科大学生物化学与分子生物学系 北京市, 100069
  • 折叠

摘要

Abstract

Ezrin protein is a member of ERM family. It not only takes part in cell proliferation, migration, adhesion and invasion, but also influences cell cycle and cell apoptosis. It is overex-pressed in lung cancer, and the overexpression is highly associated with the development and pro-gression of lung cancer. Ezrin can be used as a biomarker for the diagnosis and treatment of lung cancer. Ezrin can also serve as a new target for the treatment of lung cancer.

关键词

Ezrin/肺癌/迁移/侵袭/EMT

Key words

Ezrin/lung cancer/migration/invasion/EMT

分类

医药卫生

引用本文复制引用

林忆萍,余和芬..埃兹蛋白(Ezrin)在肺癌发生发展中的作用[J].医学分子生物学杂志,2017,14(5):301-305,5.

基金项目

首都医科大学长学制导师项目 (No. 7 NZDS2015030)This work was supported by a grant from the Long-Term Mentoring Pro-gram at Capital Medical University (No. 7 NZDS2015030) (No. 7 NZDS2015030)

医学分子生物学杂志

OACSTPCD

1672-8009

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