中国实用神经疾病杂志2017,Vol.20Issue(18):35-38,4.DOI:10.3969/j.issn.1673-5110.2017.18.011
急性脑梗死患者血液流变学及凝血功能的临床意义
Clinical significance of hemorheology and coagulation function in patients with acute cerebral infarction
徐敏 1许玉秋1
作者信息
- 1. 邳州市人民医院神经内科,江苏 邳州 221300
- 折叠
摘要
Abstract
Objective To investigate the changes and clinical significance of hemorheology and coagulation function in pa-tients with acute cerebral infarction.Methods Totally 75 cases of acute cerebral infarction were selected as the observation group, including 25 cases in mild,moderate and severe patients,respectively.Seventy-five healthy people were selected as the control group.Hemorheology and coagulation function were compared into two groups,and its changes were recorded in the observation group with different degree of cerebral infarction.Results Whole blood viscosity,whole blood low shear viscosity,plasma viscosity and hematocrit in the observation group were significantly higher than those in the control group (P <0.05 ).Plasma fibrinogen (FIB ) in the observation group were significantly higher than that in the control group (P < 0.05 ),activated partial thromboplastin time (APTT)and prothrombin time (PT)had no statistically significant difference in the two groups (P >0.05). There were statistically significant in high blood viscosity,low shear blood viscosity,plasma viscosity difference and hematocrit in severe,moderate and mild patients (P <0.05);there was statistically significant in FIB in severe,moderate and mild patients (P <0.05).Conclusion There are abnormal hemorheology and coagulation function in patients with acute cerebral infarction,and its changes are directly proportional to the severity of acute cerebral infarction.Monitoring the dynamic changes could provide refer-ence value for clinical treatment.关键词
急性脑梗死/血液流变学/凝血功能Key words
Acute cerebral infarction/Hemorheology/Coagulation function分类
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徐敏,许玉秋..急性脑梗死患者血液流变学及凝血功能的临床意义[J].中国实用神经疾病杂志,2017,20(18):35-38,4.