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昼夜节律在代谢调控中的作用

邢陈 顾晔 宋伦

军事医学2017,Vol.41Issue(7):618-622,5.
军事医学2017,Vol.41Issue(7):618-622,5.DOI:10.7644/j.issn.1674-9960.2017.07.015

昼夜节律在代谢调控中的作用

Function of circadian rhythms in regulation of metabolism

邢陈 1顾晔 1宋伦2

作者信息

  • 1. 军事医学科学院基础医学研究所军事应激医学研究室,北京 100850
  • 2. 兰州大学基础医学院病理学研究所,兰州 730000
  • 折叠

摘要

Abstract

The circadian rhythm generated by the endogenous circadian clock system depends on the feedback loop composed of a series of core clock genes (bmal1, clock, cry and per) and clock controlled genes (rev-erbα, rorα, dbp, tef and hlf) .The circadian rhythm is closely related to the body metabolism , which plays important roles in the metabolic process of the major nutrients , such as glucose and fat .Circadian rhythm disorders caused by exogenous factors will significantly increase the risk of metabolic syndrome .This paper focuses on the effect of circadian rhythms on metabolism and their roles in regulating metabolic syndrome .

关键词

昼夜节律/生物钟/能量代谢/代谢综合征

Key words

circadian rhythm/circadian clock/energy metabolism/metabolic syndrome

分类

医药卫生

引用本文复制引用

邢陈,顾晔,宋伦..昼夜节律在代谢调控中的作用[J].军事医学,2017,41(7):618-622,5.

基金项目

全军医学科研"十二五"重大资助项目(AWS14J011) (AWS14J011)

北京市自然科学基金青年资助项目(7164287) (7164287)

细胞应激生物学国家重点实验室(厦门大学)开放基金资助项目(SKLCSB2016KF010) (厦门大学)

军事医学

OA北大核心CSCDCSTPCD

1674-9960

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