检验医学与临床2017，Vol.14Issue(19)：2869-2870,2873,3.DOI:10.3969/j.issn.1672-9455.2017.19.020
宫颈上皮内瘤变与高危HPV感染病毒载量的相关性探讨
Study on correlation between cervical intraepithelial neoplasia and high-risk HPV infection viral load
张贤 1王丽娟 1张焕潮1
作者信息
- 1. 南通大学附属南京江北人民医院妇产科,南京 210048
- 折叠
摘要
Abstract
Objective To investigate the correlation between cervical intraepithelial(CIN)and high-risk human papillomavirus (HR-HPV)infection viral load.Methods The clinical data of 1528 women undergoing physical examination in our hospital from March 2014 to July 2016 were retrospectively analyzed.The results of cervical cytology and HR-HPV examination were compared, and the correlation between CIN and viral load of HR-HPV infection was analyzed.Results Among 1528 women undergoing the physical examination,HR-HPV was detected in 313 cases,the positive rate was 20.48%,152 cases were positive in pathological ex-amination,and the positive rate was 9.94%.Among 152 cases of positive pathological examination,111 cases were infected by HR-HPV with the infection rate of 73.03%.The HPV infection viral load had statistical difference among different CIN grades (P <0.05).The higher the CIN level,the higher the HPV viral load,the difference between various groups was statistically significant (P <0.05).The trend chi square test was performed on CIN classification and virus infection rate,the results showed that the high-er the CIN grade,the higher the viral infection rate,the difference was statistically significant(χ2 =34.613,P <0.05).The Pearson correlation analysis showed that CIN grading was positively correlated with HR-HPV viral load,and the difference was statistically significant (r=0.815,P <0.05).Conclusion The CIN degree is positively correlated with HR-HPV viral load.关键词
宫颈上皮内瘤变/高危型人乳头瘤病毒/病毒载量/相关性Key words
cervical intraepithelial neoplasia/high-risk human papillomavirus viral/viral load/correlation引用本文复制引用
张贤,王丽娟,张焕潮..宫颈上皮内瘤变与高危HPV感染病毒载量的相关性探讨[J].检验医学与临床,2017,14(19):2869-2870,2873,3.
