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生物人工肝和肝移植:肝衰竭治疗新模式

丁义涛

临床肝胆病杂志2017,Vol.33Issue(9):1693-1698,6.
临床肝胆病杂志2017,Vol.33Issue(9):1693-1698,6.DOI:10.3969/j.issn.1001-5256.2017.09.013

生物人工肝和肝移植:肝衰竭治疗新模式

Bioartificial liver and liver transplantation: new modalities for the treatment of liver failure

丁义涛1

作者信息

  • 1. 南京大学医学院附属鼓楼医院肝胆外科,南京210008
  • 折叠

摘要

Abstract

The main features of liver failure are extensive necrosis of hepatocytes,rapid disease progression,and poor prognosis,and at present,there are no effective drugs and methods for the treatment of liver failure.This article summarizes four treatment methods for liver failure,i.e.,medical treatment,cell transplantation,liver transplantation,and artificial liver support therapy,and elaborates on the existing treatment methods.The current medical treatment regimen should be optimized;cell transplantation has not been used in clinical practice;liver transplantation is the most effective method,but it is limited by donor liver shortage and high costs;artificial liver can effectively remove toxic substances in human body.Therefore,this article puts forward artificial liver as a transition for liver transplantation;artificial liver can buy time for liver regeneration or liver transplantation and prolong patients' survival time and thus has a promising future.The new treatment modality of bioartificial liver combined with liver transplantation may bring good news to patients with liver failure.

关键词

肝功能衰竭/肝移植/肝,人工/治疗

Key words

liver failure/liver transplantation/liver, artificial/therapy

分类

医药卫生

引用本文复制引用

丁义涛..生物人工肝和肝移植:肝衰竭治疗新模式[J].临床肝胆病杂志,2017,33(9):1693-1698,6.

临床肝胆病杂志

OA北大核心CSTPCD

1001-5256

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