生命科学研究2017，Vol.21Issue(4)：370-376,7.DOI:10.16605/j.cnki.1007-7847.2017.04.016
阿尔茨海默病早期诊断的体液生物标志物
Biomarkers for Early Diagnosis of Alzheimer's Disease in Body Fluids
摘要
Abstract
Alzheimer's disease (AD),a neurodegenerative disease,is a common cause of dementia in late life and characterized by progressive loss of memory and cognition.The pathogenesis of AD lasts for decades but is difficult to be accurately detected.Given no cure for AD so far,early diagnosis and intervention are particularly important.More sensitive and convenient diagnostic methods are still under investigation.Recently,more and more attention has been paid to biomarkers in body fluids (especially blood) as effective methods for early diagnosis of AD.Here,the AD-related biomarkers in cerebrospinal fluid,blood and urine were summarized,and their potential applications and prospects were also discussed.关键词
阿尔茨海默病(AD)/早期诊断/生物标志物/体液Key words
Alzheimer's disease (AD)/early diagnosis/biomarkers/blood fluids分类
医药卫生引用本文复制引用
樊璠,龙建纲,刘健康..阿尔茨海默病早期诊断的体液生物标志物[J].生命科学研究,2017,21(4):370-376,7.基金项目
国家重点基础研究发展计划项目(973计划项目)(2015CB856302) （973计划项目）
