Abstract
Objective To analyze the correlation between the location of infarctions and pathogenesis among patients of paramedian pontine infarction without basilar artery stenosis .Methods We selected 150 patients with acute phase para-median pontine infarction ( PPI) ,the patients without basilar artery stenosis were divided into two groups: dPPI-BAS and vPPI-BAS.PPI+BAS were chosen as control group .Age,sex,smoking,alcohol drinking,hyperlipidaemia,hyperhomocys-teinemia,coronary atherosclerotic heart disease,diabetes,ICAS,EAAS,basal artery high signal,infarcts level ≥2 layers, END,hypertension,lacunars cerebral infarction and leukoaraiosis were compared between groups .Results 150 patients were enrolled,among them 41 patients with dPPI-BAS (27.3％),65 patients with vPPI-BAS (43.3％),44 patients with PPI+BAS (29.3％).Age,sex,smoking,alcohol drinking,hyperlipidaemia and hyperhomocysteinemia weren 't have statis-tically significant differences between groups (P>0.05),coronary atherosclerotic heart disease ,diabetes,hypertension,LA scales,ICAS,EAAS,basal artery high signal,Infarcts level ≥2 layers and END had statistically significant differences (P<0.05).All the factors weren't have statistically significant between vPPI-BAS group and PPI +BAS group(P>0.05). Compared to PPI +BAS group,the dPPI-BAS group had lower prevalences of coronary atherosclerotic heart disease ,diabe-tes,ICAS,EAAS,basal artery high signal ,infarcts level≥2 layers and END,but had higher prevalences of hypertension ,LA and LI( P<0.05).Between vPPI-BAS group and dPPI-BAS group,vPPI-BAS group had higher prevalences of ICAS , EAAS,Infarcts level ≥2 layers and END ,while dPPI-BAS group had higher prevalences of hypertension ,LA and LI ( P<0.05).Multi-factor Logistic regression analysis shows:LA scales was independent prognostic factor for dPPI-BAS.Con-clusion The mechanism of vPPI-BAS was more likely atherosclerosis , and the mechanism of dPPI-BAS was more likely small vessel disease .关键词
脑桥旁正中梗死/动脉粥样硬化/小血管病Key words
Paramedian pontine infarction/Atherosclerosis/Small vessel disease分类
医药卫生
