中国感染控制杂志2017，Vol.16Issue(10)：936-940,5.DOI:10.3969/j.issn.1671-9638.2017.10.009
2012—2015年医院血流感染病原菌分布及耐药性变迁
Changes in distribution and antimicrobial resistance of pathogens causing bloodstream infection in 2012-2015
摘要
Abstract
Objective To investigate the changes in distribution and antimicrobial resistance of pathogens causing bloodstream infection in a hospital in 2012-2015.Methods Pathogenic bacteria isolated from blood culture in a hospital microbiology laboratory between January 2012 and December 2015 were collected and divided into 2012-2013 group and 2014-2015 group,distribution characteristics,constitute,and antimicrobial susceptibility of two groups were compared.Results Gram-negative bacteria were the main pathogens isolated during two periods,ac-counting for 54.96% and 54.66% respectively,there was no significant differences in pathogen distribution between two groups (P >0.05).Gram-positive cocci had a high sensitivity to vancomycin and linezolid,resistant rates were both 0;resistance rates of coagulase negative staphylococci to oxacillin were all >80%,resistance to penicillin was also >90%;Enterobacteriaceae was highly sensitive to imipenem and meropenem,but resistance strains had ap-peared;Acinetobacter baumannii was sensitive to minocycline during two periods,resistance rates were 35.90% and 34.55% respectively,resistance rates to other antimicrobial agents were also high (>75%).Conclusion The iso-lation rate of drug-resistant pathogenic strains causing bloodstream infection is high,monitoring on bacterial resistance is helpful for guiding rational use of antimicrobial agents in clinic.关键词
血流感染/病原菌/抗药性,微生物/耐药性Key words
bloodstream infection/pathogen/drug resistance,microbial分类
医药卫生引用本文复制引用
徐腾飞,刘志武,金凤玲..2012—2015年医院血流感染病原菌分布及耐药性变迁[J].中国感染控制杂志,2017,16(10):936-940,5.基金项目
甘肃省科技厅青年科技基金资助项目(1506RJYA261) （1506RJYA261）
