中国临床药理学与治疗学2017，Vol.22Issue(8)：852-858,7.
复方鹿角乳痛宁胶囊与原基础方的药效学对比研究
Comparison of pharmacodynamics of Fufang lujiao rutongning capsule and its original formula
摘要
Abstract
AIM:To compare the therapeutic and analgesic effect of improved Fufang lujiao rutongning capsule and its original formula on hyperplasia of mammary glands in rats.METHODS:The model of mammary glands hyperplasia was induced by intramuscular injection of estradiol and progesterone so as to evaluate the action receptors in breast issues and the serum levels of hormone and to compare the therapeutic effect of both formulas.In the analgesic experiment,glacial acetic acid was used to induce writhing to compare the time of latency,number of writhing and of analgesic rate of the two formulas.RESULTS:Both formulas of Rutongning capsule could alleviate the breast hyperplasia,while the improved formula presented better therapeutic and analgesic effect.CONCLUSION:Fufang lujiao rutongning capsule is better than Rutongning capsule for controlling hyperplasia pain.关键词
复方鹿角乳痛宁胶囊/乳痛宁胶囊/乳腺增生/镇痛Key words
Fufang lujiao rutongning capsule/Rutongning capsule/hyperplasia of mammary glands/analgesia分类
医药卫生引用本文复制引用
冷晓微,Rita,李敏,张桐,任立群,范志民..复方鹿角乳痛宁胶囊与原基础方的药效学对比研究[J].中国临床药理学与治疗学,2017,22(8):852-858,7.基金项目
长春市科技计划项目(14KG048) （14KG048）
