中国现代医学杂志2017，Vol.27Issue(23)：61-64,4.DOI:10.3969/j.issn.1005-8982.2017.23.012
输尿管软镜与经皮肾镜治疗肾结石的相关研究
Comparative study of flexible ureteroscopy and percutaneous nephroscopy for renal calculi
摘要
Abstract
Objective To compare the effect of ureteroscopy and percutaneous nephrolithotomy on postoperative renal function, coagulation function and oxidative stress products in patients with renal calculi. Methods Fifty-two patients who were diagnosed with renal calculus in our hospital were collected. The patients were randomly divided into percutaneous nephroscopic group and ureteroscopic group, 26 cases in each group. The percutaneous nephroscopic group was given percutaneous holmium laser lithotripsy through nephroscope, the ureteroscopic group was treated with nephroscopic holmium laser lithotripsy. After treatment, the indexes of renal function, coagulative function and oxidative stress and treatment effect were detected in all patients. Results After operation, compared with percutaneous nephroscopic group, the serum levels of creatinine, NGAL, Cys C and MDA, and the α and MA values of thromboelastogram (TEG) were lower; and the R and K values of TEG and serum GSH-Px level were higher; the amount of blood loss was smaller and the rate of stone clearance was higher in the ureteroscopic group; the differences were statistically significant ( < 0.05). Conclusions Compared with percutaneous nephroscopic holmium laser lithotripsy, ureteroscopic holmium laser lithotripsy has less influence on renal function, blood coagulative function and the oxidative stress reaction in patients with kidney stones; the amount of intraoperative blood loss is smaller, the rate of stone clearance is higher, which have guiding significance for clinic.关键词
输尿管镜钬激光碎石术/经皮肾镜钬激光碎石术/肾结石/肾功能/凝血功能/氧化应激产物Key words
ureteroscopy/percutaneous nephrolithotomy/renal calculus/renal function/coagulative function/oxidative stress products分类
医药卫生引用本文复制引用
杨杰,尹小兵..输尿管软镜与经皮肾镜治疗肾结石的相关研究[J].中国现代医学杂志,2017,27(23):61-64,4.基金项目
贵州省科学技术进步项目(No:2011J_038) （No:2011J_038）
