国际口腔医学杂志2017，Vol.44Issue(5)：514-518,5.DOI:10.7518/gjkq.2017.05.004
慢性牙周炎与神经退行性疾病相关性的研究进展
Research progress on the correlation between chronic periodontitis and neurodegenerative diseases
李琳 1王丹 2赵曼竹 1唐明3
作者信息
- 1. 重庆医科大学附属第一医院口腔科 重庆400016
- 2. 重庆市协尔口腔诊所 重庆400016
- 3. 重庆医科大学附属口腔医院口腔预防科 重庆400016
- 折叠
摘要
Abstract
Neurodegenerative diseases mainly encompass Alzheimer's disease(AD),Parkinson's disease(PD),Huntington's disease(HD) and etc,characterized by progressive movement disorder,sensory disturbance and cognitive dysfunctin,which mostly develop in the elderly and there is no effective cure measures.Accumulating researches have demonstrated that neuroinflammation,systemic inflammationand immune disorder may be involved in onset and development of the diseases.Studies have shown that as a local bacterial infectious disease,chronic periodontitis possibly affect neurodegenerative diseases by periodontal pathogens,inflammatory mediators and oxidative stress.This review focuses on the correlation between chronic periodontitis and neurodegenerative diseases,for providing a new idea for prevention and treatment of neurodegenerative diseases.关键词
慢性牙周炎/牙周致病菌/神经退行性疾病/神经炎症/免疫Key words
chronic periodontitis/periodontal bacteria/neurodegenerative disease/neuroinflammation/immunity分类
医药卫生引用本文复制引用
李琳,王丹,赵曼竹,唐明..慢性牙周炎与神经退行性疾病相关性的研究进展[J].国际口腔医学杂志,2017,44(5):514-518,5.
