日用化学工业2017，Vol.47Issue(9)：497-501,5.DOI:10.13218/j.cnki.csdc.2017.09.004
十二烷基羟丙基磺基甜菜碱对产膜表皮葡萄球菌粘附作用的影响
Effect of dodecyl hydroxypropyl sulfobetaine on adhesion of Staphylococcus epidermidis biofilm formation bacteria
摘要
Abstract
An investigation of inhibitory effects of surfactant dodecyl hydroxypropyl sulfobetaine (DSB)against adhesion of Staphylococcus epidermidis biofilm formation bacteria was conducted in order to find possible new research direction and treatment method of S. epidermidis biofilm bacteria associated infection. Vancomycin is applied as positive control,XTT reduction assay is used to evaluate the effect of DSB on the initial adhesion of S. epidermidis. The presented results show that DSB displays a significantly inhibitory effect on the initial adhesion of S. epidermidis at the mass concentration of 64 mg/L. After the experimental starting materials are pretreated by DSB at the mass concentration of 512,256 and 128 mg/L,the initial adhesion of S. epidermidis is significantly inhibited. Therefore,experimental results indicate that DSB has an significantly inhibitory effects on the initial adhesion in the process of biofilm formation of S. epidermidis.关键词
表面活性剂/十二烷基羟丙基磺基甜菜碱/粘附/表皮葡萄球菌/生物被膜Key words
surfactant/dodecyl hydroxypropyl sulfobetaine/adhesion/Staphylococcus epidermidis/biofilm分类
化学化工引用本文复制引用
段强军,花私齐,官妍..十二烷基羟丙基磺基甜菜碱对产膜表皮葡萄球菌粘附作用的影响[J].日用化学工业,2017,47(9):497-501,5.基金项目
安徽省自然科学基金资助项目(1508085MH200) （1508085MH200）
安徽省教育厅自然科学研究项目(KJ2013Z163) （KJ2013Z163）
