畜牧兽医学报2017,Vol.48Issue(9):1572-1578,7.DOI:10.11843/j.issn.0366-6964.2017.09.002
支原体分泌蛋白研究进展
Progress on Secretory Proteins of Mycoplasma
摘要
Abstract
Mycoplasma is a critical pathogen of humans and animals.Due to lacking of highly effective drugs and vaccines,these diseases cause serious economic losses.The unknown pathogenesis and immunologic response restrict the development of novel drugs and vaccines.Secretory proteins are involved in direct communication between pathogens and hosts and usually considered as the key factors of virulence and immunity.Therefore they are potential targets of novel drugs and vaccines.But the study of secretory proteins of Mycoplasma has just started and only a few of Mycoplasma secretory proteins have been identified.In addition,the functions of secretory proteins in pathogenesis and immunity are mostly unknown.This paper reviewed the identified secretory proteins of Mycoplasma,their secretion pattern,and the methods used in related research,in order to provide some support to future study of Mycoplasma secretory proteins.关键词
支原体/分泌蛋白/靶标/疫苗/致病性/免疫Key words
Mycoplasma/secretory protein/target/vaccine/pathogenesis/immunity分类
农业科技引用本文复制引用
胡古月,赵刚,陈颖钰,郭爱珍..支原体分泌蛋白研究进展[J].畜牧兽医学报,2017,48(9):1572-1578,7.基金项目
国家自然科学基金国际(地区)合作交流项目(3161101352) (地区)
国家重点研发计划(2016YFD0500906) (2016YFD0500906)
现代农业(肉牛牦牛)产业技术体系专项经费(CARS-38) (肉牛牦牛)