中国现代医学杂志2017，Vol.27Issue(20)：11-15,5.DOI:10.3969/j.issn.1005-8982.2017.20.003
BAFF受体在人B淋巴瘤细胞中的作用研究
BAFF-R expression in B cell lymphoma
摘要
Abstract
Objective To detemine the expression of B-cell activating factor receptor (BAFF-R) in B cell lymphoma and to explore the role of BAFF-R signal transduction in B cell lymphoma.Methods Human Bcell lymphoma cell lines Raji,Daudi and BALL-1 were selected as the objects of study.BAFF-R expression was detected by flow eytometry,qRT-PCR and Western blot.Results Flow cytometry results demonstrated that BAFF-R was up-regulated in all the three cell lines,qRT-PCR and Western-blot indicated the same results.Conclusions BAFF-R expression is up-regulated in all the three B-cell lymphoma cell lines,and closely correlated to the growth and proliferation of B-cell lymphoma.关键词
B细胞活化因子/B细胞活化因子受体/B淋巴瘤细胞Key words
B-cell activating factor/ B-cell activating factor receptor/ B-cell lymphoma分类
医药卫生引用本文复制引用
王永伦,封忠昕,葛晓军..BAFF受体在人B淋巴瘤细胞中的作用研究[J].中国现代医学杂志,2017,27(20):11-15,5.基金项目
国家自然科学基金(No:81560487) （No:81560487）
贵州省科学技术基金[No:黔科合J(2011)2264] （2011）
