中国妇幼健康研究2017，Vol.28Issue(10)：1165-1167,3.DOI:10.3969/j.issn.1673-5293.2017.10.001
兰州地区早产影响因素的研究
Risk factors of preterm birth in Lanzhou area
摘要
Abstract
Objective To explore the risk factors of preterm birth , spontaneous preterm birth and iatrogenic preterm birth .Methods A retrospective study was conducted on medical data of pregnant women with full term birth or preterm birth hospitalized in Gansu Maternal and Child Health Care Hospital from January 2010 to December 2012.There were 5639 full-term births and 540 preterm births, and they were divided into full term group (≥37 gestational age ) and preterm group ( <37 gestational age ) .Risk factors of preterm birth were compared between two groups , and relevant risk factors of spontaneous preterm birth and iatrogenic preterm birth were analyzed .Results Logistic regression analysis showed that education duration (≥16 years) (OR=0.61, 95%CI:0.48-0.78) and average family monthly income (>3000 yuan) (OR=0.62, 95%CI:0.50-0.78) were protective factors of preterm birth .However, pregnancy complications such as gestational diabetes mellitus (GDM) (OR=3.97, 95%CI:1.70-9.25), hypertensive disorders in pregnancy (HDP) (OR=4.43, 95%CI:3.35-5.87) and intrahepatic cholestasis of pregnancy (ICP) (OR=4.88, 95%CI:3.25-7.32) were independent high risk factors of preterm birth .There were 340 cases of spontaneous preterm birth and 200 cases of iatrogenic preterm births in this study divided by causes .Stratified multivariate unconditional logistic regression analysis revealed that compared with full term births , iatrogenic preterm delivery was more common among multipara (OR=2.66,95%CI:1.87-3.76), GDM (OR=4.52,95%CI:1.42-14.38) and especially HDP puerpera (OR =14.19,95%CI:10.10 -19.93) , and spontaneous preterm birth happened more frequently in ICP puerpera (OR=12.875, 95%CI:12.75 -13.00).Conclusion Potential risk factors of preterm birth should be identified earlier and perinatal management should be strengthened to reduce incidence of preterm birth and improve outcomes of perinatal infants .关键词
早产/出生队列/危险因素/医源性早产/自发性早产Key words
preterm birth/birth cohort/risk factors/iatrogenic preterm birth/spontaneous preterm birth分类
医药卫生引用本文复制引用
李静,毛宝宏,丁仲军,裴建赢,王晶晶,王燕侠..兰州地区早产影响因素的研究[J].中国妇幼健康研究,2017,28(10):1165-1167,3.基金项目
甘肃省科学技术厅重点实验室专项资助项目(项目编号:1506RTSA158) （项目编号:1506RTSA158）
