摘要
Abstract
Objective To explore the treatment effect of ultrasound-guided methotrexate ( MTX) injection in embryo sac on cesarean scar pregnancy (CSP).Methods Forty-one patients with CSP treated in obstetrics and gynecology department in Weifang Maternal and Child Health Care Hospital from January 2010 to December 2015 were selected and divided into two groups according to different treatment methods, including 21 cases in study group treated with ultrasound-guided MTX injection in gestational sac and 20 cases in control group treated with uterine artery chemoembolization .Serum human chorionic gonadotropin ( HCG) was rechecked , and single dose intramuscular MTX injection was given if serum HGC dropped less than 15%after one week, and then MTX injection could be repeated .Cure rate, time for serum HCG dropping to normal level and amount of MTX administrated were compared between two groups .Results There was no significant difference in cure rate (χ2 =0.212, P=0.645), time for serum HCG dropping to normal level (t=0.763, P=0.801) and amount of administrated MTX (χ2 =0.200, P =0.655 ) between two groups .Patients with gestational sac bigger than 3cm occupied 66.67%(6/9) in failed cases, which was significantly higher than that ( 9.38%, 3/32 ) in successful cases and difference was statistically significant (χ2 =10.321, P=0.001).Patients with type II CSP accounted for 70.00% (7/10) in failed cases, which was significantly higher than that (9.38%, 3/32) in successful cases and difference had statistical significance (χ2 =14.306, P=0.000). Conclusion Treatment effect of ultrasound-guided methotrexate ( MTX) injection in embryo sac on CSP is assuring .Its operation is easy and its requirement on equpiment is low .It can be used as preferred method for treating patients with suitable conditions in primary hospital.关键词
剖宫产瘢痕妊娠/甲氨蝶呤/超声引导/子宫动脉栓塞Key words
cesarean scar pregnancy ( CSP)/methotrexate ( MTX)/ultrasound-guided/uterine artery chemoembolization分类
医药卫生
