华西口腔医学杂志2017，Vol.35Issue(5)：533-537,5.DOI:10.7518/hxkq.2017.05.017
人乳牙牙髓干细胞在干细胞治疗中的应用
Clinical applications of stem cells from human exfoliated deciduous teeth in stem cell therapy
摘要
Abstract
Stem cells from human exfoliated deciduous teeth (SHED) are one category of dental stem cells. They belong to ectodermal mesenchymal stem cells. As an ideal stem cell source, SHED possess great potential in stem cell therapy. This review demonstrates the biological characteristics and advantages of SHED in stem cell therapy and discusses its multiple functions in tissue regeneration and repair, including multiple differentiation potentiality, cell secretion of cytokines, and immunomodulatory ability. Furthermore, this article introduces the main findings regarding the potential clinical applications of SHED to a variety of diseases. This article demonstrates research progress in dentin-pulp regeneration, maxillofacial bone regeneration, and treatment of nervous system and immune system diseases with SHED for stem cell transplantation.关键词
人乳牙牙髓干细胞/干细胞治疗/临床应用Key words
stem cells from human exfoliated deciduous teeth/stem cell therapy/clinical applications分类
医药卫生引用本文复制引用
李晓霞,方滕姣子,余湜,赵玉鸣,葛立宏..人乳牙牙髓干细胞在干细胞治疗中的应用[J].华西口腔医学杂志,2017,35(5):533-537,5.基金项目
国家自然科学基金(81541110) National Natural Science Foundation of China (81541110). （81541110）
