四川大学学报（医学版）2017，Vol.48Issue(5)：740-744,5.
颅内动脉狭窄伴未破裂颅内动脉瘤的临床特点及危险因素分析
Analysis on Clinical Characteristic and Risk Factors of Patients Coexistence of Cerebral Artery Stenosis with Unruptured Intracranial Aneurysm
摘要
Abstract
Objective To analyze the incidence of intracranial unruptured aneurysms in patients with intracranial artery stenosis,clinical features,and investigate the risk factors for unruptured intracranial aneutysms.Methods Medical records from all patients performed with digital subtraction angiography (DSA) who had been treated at Peking University Third Hospital,China,from January 2012 to December 2015 were retrospectively reviewed to identify cases coexistence with cerebral artery stenosis and unruptured intracranial aneurysm.Results Of 273 patients with cerebral artery stenosis (≥50％),intracranial unruptured aneurysms was observed in 17 eases (6.23％) from age of 45 to 78,among them 8 (47.06％) were female and 9 (52.94％) were male.The incidence of unruptured intracranial aneurysm in male patients was 4.17％ (9/216),and that of female was 14.4％ (8/57).There was statistically significant difference between the male and female incidence of intracranial aneurysm (P＜0.05).Of these 17 patients,16 (94.12％) aneurysms were located in the internal carotid artery (ICA) system,1 (5.88％) aneurysm was located at the tip of the basilar artery.In 11 cases (64.71％),aneurysms were located at the distal of the stenotic vessels,2 (11.76％) were located at the proximal of the stenotic vessels,and 4 cases (23.53％) of which the aneurysm and stenosis were not in the same artery.Logistic multivariate analysis showed that gender was an independent risk factor for aneurysms in patients with cerebral arterial stenosis.Conclusion In the intracranial artery stenosis atients,the possibility of the occurrence of the aneurysm is much higher than the general population,and women were more prominent than man.Sex is an independent risk factor for aneurysms in patients with cerebral arterial stenosis.关键词
未破裂颅内动脉瘤/颅内动脉狭窄/颈内动脉狭窄Key words
Unruptured Intracranial aneurysm/Cerebral artery stenosis/Internal carotid stenosis引用本文复制引用
赵海燕,韩金涛,樊东升..颅内动脉狭窄伴未破裂颅内动脉瘤的临床特点及危险因素分析[J].四川大学学报（医学版）,2017,48(5):740-744,5.基金项目
国家自然科学基金(No.81471184)资助 （No.81471184）
