实用临床医药杂志2017，Vol.21Issue(17)：6-8,3.DOI:10.7619/jcmp.201717002
腹腔镜与开腹直肠癌扩大根治术对老年患者细胞免疫功能的影响
Effect of laparoscopic and open extended radical resection of rectal carcinoma on cellular immune function of elderly patients
摘要
Abstract
Objective To investigate the effect of laparoscopic and open extended radical resection of rectal carcinoma on cellular immune function of elderly patients.Methods A total of 60 elderly patients with colorectal cancer were enrolled and divided into two groups according to therapeutic methods.The control group was treated with open extended radical resection of rectal carcinoma,and the study group was treated with laparoscopic extended radical resection of rectal carcinoma.The fasting venous blood of all patients 1 day before operation and 1,3 and 5 days after operation were measured,and the levels of T lymphocyte subsets (CD3 +,CD4 +,CD8 +) were measured and compared.Results Compared with the levels of indexes 1 day before operation,CD3 +,CD4 +,CD8 + in the control group 1,3 and 5 days after operation and 1,3 days after operation in study group significantly decreased (P ＜ 0.05).The 1,3 and 5 days after operation,the CD3 +,CD4 + and CD8 + in study group were significantly higher than the control group (P ＜ 0.05).Conclusion Laparoscopic and open extended radical resection of rectal carcinoma have a certain impact on cellular immune function,but effect of laparoscopic extended radical resection of rectal carcinoma is relatively less,which is conducive to the orotection of cellular immune function.关键词
腹腔镜/开腹直肠癌扩大根治术/细胞免疫功能/老年患者Key words
laparoscopy/open extended radical resection of rectal carcinoma/cellular immune function/elderly patients分类
医药卫生引用本文复制引用
吕正耀,熊治国,丁丁,徐迎欣..腹腔镜与开腹直肠癌扩大根治术对老年患者细胞免疫功能的影响[J].实用临床医药杂志,2017,21(17):6-8,3.基金项目
国家863计划课题(2006AA02Z4B9) （2006AA02Z4B9）
