环境与职业医学2017，Vol.34Issue(9)：847-851,5.DOI:10.13213/j.cnki.jeom.2017.16822
全氟辛烷磺酸神经毒性研究进展
Current neurotoxicity research on perfluorooctane sulfonate
摘要
Abstract
Perfluorooctane sulfonate (PFOS) as an extremely persistent and refractory organic pollutant has attracted increasing attention from researchers in various fields in recent years.This paper reviewed PFOS transport and metabolism,neurotoxicity,and possible mechanisms,including inhibiting neuron growth & differentiation and brain development,affecting synaptogenesis and plasticity,suppressing neurotransmitter production,disturbing ion channels,and inducing neuroinflammation & oxidative stress in neuron cells.关键词
全氟辛烷磺酸(PFOS)/代谢/神经毒性/毒作用机制Key words
perfluorooctane sulfonate (PFOS)/metabolism/neurotoxicity/toxic mechanism分类
医药卫生引用本文复制引用
陈晓旭,姜声扬..全氟辛烷磺酸神经毒性研究进展[J].环境与职业医学,2017,34(9):847-851,5.基金项目
国家自然科学基金项目(编号:81573188) （编号:81573188）
