四川中医2017，Vol.35Issue(9)：119-122,4.
中药化栓汤联合低分子肝素对老年髋关节置换术后凝血相关指标及DVT的影响
Effect of Huashuan Decoction Combined with Low Molecular Heparin on Coagulation Related Indexes and DVT for Elderly Patients Undergoing Hip Replacement
宋凯林 1何宗亮 2汪娟1
作者信息
- 1. 鄂东医疗集团黄石市中心医院(湖北理工学院附属医院)急诊外科,湖北黄石435000
- 2. 鄂东医疗集团黄石市中心医院(湖北理工学院附属医院)创伤外科,湖北黄石435000
- 折叠
摘要
Abstract
Objective:To observe the effect of traditional Chinese medicine (TCM) Huashuan Decoction combined with low molecular weight heparin (LMWH) on coagulation related indexes and postoperative DVT (deep venous thrombosis) for elderly patients undergoing hip replacement.Methods:A total of 92patients with hip fractures who were admitted to our hospital between October 2011and October 2014were divided into LMWH group and combined traditional Chinese and western medicine group,46cases in each group according to postoperative intervention methods.Both groups were treated with LMWH after the operation,and the latter were additionally treated with TCM Huashuan Decoction.The changes of coagulation related indexes [platelet count (PLT),prothrombin time (PT),plasma fibrinogen (FIB),activated partial thromboplastin time (APTT),thrombin time (TT)],D-dimer (D-D) level and the degree of limb swelling before and after treatment were observed.The incidence rates of DVT and adverse reactions were recorded.Results:The levels of PT,APTT and TT were significantly higher in the combined traditional Chinese and western medicine group than the LMWH group (P＜0.05).The diameter of the superior margin of the patella was significantly shorter in the combined traditional Chinese and western medicine group than the LMWH group (P＜0.05).The incidence rates of DVT and adverse reactions were lower in the combined traditional Chinese and western medicine group than the LMWH group (2.17％ and 4.35％ vs 15.22％ and 17.39％) (P＜0.05).Conclusion:The effect ofTCM Huashuan Decoction combined with LMWH is significant in the treatment of DVT in patients with hip fractures after hip replacement.It can inhibit thrombosis by relieving the hypercoagnlable state,safe and reliable,without increasing adverse reactions.关键词
化栓汤/低分子肝素/髋关节/骨折/下肢深静脉血栓Key words
Huashuan Decoction/Low molecular heparin/Hip joint/Fracture/Deep venous thrombosis of lower extremity分类
医药卫生引用本文复制引用
宋凯林,何宗亮,汪娟..中药化栓汤联合低分子肝素对老年髋关节置换术后凝血相关指标及DVT的影响[J].四川中医,2017,35(9):119-122,4.
