应用化学2017，Vol.34Issue(10)：1161-1171,11.DOI:10.11944/j.issn.1000-0518.2017.10.170163
含有苯磺酰胺基团1,2,4-三唑和噻二唑类化合物的设计、合成及抑菌活性
Design,Synthesis and Fungicidal Bioactivity of 1 ,2 ,4-Triazoles or Thiadiazoles Containing a Benzenesulfonamide Moiety
摘要
Abstract
In order to explore efficient,low toxic and eco-friendly fungicides,a series of 1,2,4-triazole and thiadiazole derivatives containing benzenesulfonamide moieties was designed and synthesized. Their chemical structures were confirmed by nuclear magnetic resonance spectroscopy (NMR ), mass spectrometry and elemental analysis. Preliminary fungicidal bioassay in vitro was carried out against seven plant pathogenic fungi and the results showed that compounds 10 exhibited moderate fungicidal activities,especially 10a,10g and 10 n demonstrated similar high inhibition rate against Fusarium moniliforme in comparison with commercial Azoxystrobin.关键词
三唑/噻二唑/苯磺酰胺/抑菌活性Key words
triazole/thiadiazole/benzenesulfonamide/fungicidal activity分类
化学化工引用本文复制引用
陈明桂,周莎,李正名,华学文,魏巍,张冬凯,刘明,吴长春,周沙,李玉新,王宝雷..含有苯磺酰胺基团1,2,4-三唑和噻二唑类化合物的设计、合成及抑菌活性[J].应用化学,2017,34(10):1161-1171,11.基金项目
国家自然科学基金(21272129)项目资助 Supported by the National Natural Science Foundation of China(No. 21272129) （21272129）
