中国动脉硬化杂志2017，Vol.25Issue(9)：904-908,5.
遵义汉族白细胞介素6基因-572C/G多态与混合型高脂血症的相关性
Association of interleukin-6 gene-572C/G polymorphism with combined hyperlipidemia of the Han Nationality in Zunyi
摘要
Abstract
Aim To investigate the relativity of interleukin-6 gene-572C/G polymorphism with combined hyperlipidemia in Zunyi Han Nationality.Methods-572C/G polymorphism of 100 combined hyperlipidemia patients and 100 healthy individuals were tested by sequencing after polymerase chain reaction.Results Age,gender and blood sugar had no statistical differences between patients group and normal group,but blood lipid index of combined hyperlipidemia patients was higher than healthy individuals(P＜0.05).The genotype frequency and allele gene frequency of IL-6 gene-572C/G showed no correlation between patients group and normal groups (P＞0.05).Total cholesterol (TC),low density lipoprotein cholesterol (LDLC),triglyceride (TG)/high density lipoprotein cholesterol (HDLC) and TC/HDLC were different between CC and CG+GG genotype in the normal group(P＜0.05);others had no differences among the two groups.Conclusion There was no relativity between IL-6 gene-572C/G polymorphism and combined hyperlipidemia in Zunyi Han Nationality.The-572G gene was not an independent risk factor for combined hyperlipidemia.关键词
白细胞介素6基因/-572C/G多态/混合型高脂血症/遵义汉族Key words
Interleukin-6 gene/-572C/G polymorphism/Combined hyperlipidemia/Zunyi Han Nationality分类
医药卫生引用本文复制引用
吕纯莉,张志敏,耿争光,杨昌伟,肖代敏..遵义汉族白细胞介素6基因-572C/G多态与混合型高脂血症的相关性[J].中国动脉硬化杂志,2017,25(9):904-908,5.基金项目
贵州省科技厅项目(黔科合J字LKZ[2012] 39号) （黔科合J字LKZ[2012] 39号）
遵义医学院大学生创新创业训练计划项目(院发[2014]5828) （院发[2014]5828）
