中国动脉硬化杂志2017，Vol.25Issue(9)：953-956,4.
斑块内泡沫细胞外迁功能障碍的研究进展
Research progress of the dysfunction in foam cell emigration from plaques
摘要
Abstract
The formation and inhibited emigration of foam cells are the key events in malignant remodeling of artery plaques.Advanced glycation end products (AGE) play an important role in the course of diabetes-accelerating atherosclerotic progression.Based on the latest international research progress and our existing results,this paper elaborated the mechanism of CD36 modulating foam cell emigration from plaques inhibited by Nε-carboxymethyl-Lysine,which would provide a new starting point for the treatment strategy of targeting foam cell migration mechanism in the future.关键词
糖基化终末产物/清道夫受体/泡沫细胞/细胞迁移/动脉粥样硬化Key words
Advanced glycation end products/CD36/Foam cell/Cell migration/Atherosclerosis分类
医药卫生引用本文复制引用
王中群,李丽华,严金川,叶斐,邵晨..斑块内泡沫细胞外迁功能障碍的研究进展[J].中国动脉硬化杂志,2017,25(9):953-956,4.基金项目
国家自然科学基金(81370408),江苏省自然科学基金(BK20131246),江苏省卫生厅项目(Q201308,QNRC2016836),镇江市社会发展项目(SH2015038,SH2015023),卫生部核医学重点实验室、江苏省分子核医学重点实验室开放课题(KF201504),江苏大学临床专项(JDLCZX001) （81370408）
