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骨保护素与动脉粥样硬化的研究进展

许赫 刘长山 窦建新

中国动脉硬化杂志2017,Vol.25Issue(9):968-972,5.
中国动脉硬化杂志2017,Vol.25Issue(9):968-972,5.

骨保护素与动脉粥样硬化的研究进展

Research progress of osteoprotegerin and atherosclerosis

许赫 1刘长山 2窦建新2

作者信息

  • 1. 潍坊医学院临床医学院,山东省潍坊市261000
  • 2. 潍坊市人民医院内分泌科,山东省潍坊市261000
  • 折叠

摘要

Abstract

A soluble glycoprotein,termed osteoprotegerin,is a novel member of the tumor necrosis factor receptor superfamily.Recent studies have shown that osteoprotegerin is not only involved in bone metabolism,but also closely related to energy metabolism in vivo,glycolipid metabolism.And it is closely related to atherosclerosis and glycolipid metabolism disorders,cardiovascular and microvascular diseases.It is not clear that the mechanism is involved in the occurrence and progression of atherosclerosis by regulating glucose and lipid metabolism,endothelial function,inhibiting vascular calcification,inhibiting inflammation,inhibiting apoptosis and so on.

关键词

骨保护素/动脉粥样硬化/糖脂代谢

Key words

Osteoprotegerin/Atherosclerosis/Glycolipid metabolism

分类

医药卫生

引用本文复制引用

许赫,刘长山,窦建新..骨保护素与动脉粥样硬化的研究进展[J].中国动脉硬化杂志,2017,25(9):968-972,5.

基金项目

山东省优秀中青年科学家科研奖励基金项目(2014BSA07014) (2014BSA07014)

中国动脉硬化杂志

OACSTPCD

1007-3949

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