中国实用内科杂志2017，Vol.37Issue(9)：822-825,4.DOI:10.19538/jnk2017090109
心脏外科术后急性肾损伤行日间连续性肾脏替代治疗死亡危险因素分析
Risk factors of death in patients requiring day-time continuous renal replacement therapy for acute kidney injury after cardiac surgery
摘要
Abstract
Objective To study the risk factors of death and analyze the changes of the factors after day-time continuous renal replacement therapy(DCRRT) in AKI patients requiring DCRRT after cardiac surgery.Methods We reviewed the clinical data of the 42 AKI patients who received DCRRT after cardiac surgery in cardiovascular surgery of the First Affiliated Hospital of China Medical University,and divided them into two groups:survivors group(n=22)and non-survivors group(n=20).Univariate analysis and multivariable logistic regression were used to identify risk factors of death and we used paired t test to analyze the changes of the factors after DCRRT.Results Thefatality ratio of patients who required DCRRT after cardiac surgery was47.6％(20/42).There was statistical difference in the following factors between survivors and non-survivors:low cardiac output syndrome,age,the time of CPB,etc(P＜0.05).There was also statistical difference in the heart rate,mean arterial pressure,renal function and so on(P＜0.01).Multivariable logistic regression had identified the following factors as independent risk factors:mean arterial blood pressure and the density of bicarbonate in blood serum before DCRRT.Obvious improvements in homodynamic and renal function were found after D CRRT.Conclusion The renal function is improved and the homodynamic status is more stable after DCRRT.Mean arterial blood pressure and the density of bicarbonate in blood serum before DCRRT are the independent protective factors.关键词
肾脏替代治疗/心脏外科手术/急性肾损伤Key words
renal replacement therapy/cardiac surgery/acute kidney injury分类
医药卫生引用本文复制引用
徐天华,魏敏,邵明磊,姚丽..心脏外科术后急性肾损伤行日间连续性肾脏替代治疗死亡危险因素分析[J].中国实用内科杂志,2017,37(9):822-825,4.基金项目
国家“十二五”科技支撑计划项目子课题(2011BAI10B02) （2011BAI10B02）
辽宁省科技厅社会发展攻关计划(2013225303) （2013225303）
辽宁省教育厅高等学校科研项目(L2011134) （L2011134）
卫生公益性行业科研专项(201502010) （201502010）
