中国现代医学杂志2017，Vol.27Issue(21)：75-78,4.DOI:10.3969/j.issn.1005-8982.2017.21.014
血清前白蛋白/总胆红素比值对肝衰竭患者预后的预测价值
Prognostic value of serum prealbumin/total bilirubin ratio in patients with liver failure
赵紫烟 1安雪青 1史丽 1童国相2
作者信息
- 1. 天津市第五中心医院,天津300450
- 2. 长沙医学院附属医院,湖南长沙410219
- 折叠
摘要
Abstract
Objective To explore the prognostic value of prealbumin/total bilirubin ratio in patients with liver failure.Methods The clinical data of 152 patients with liver failure in our hospital from January 2008 to December 2015 were retrospectively analyzed.Log-Rank test was used for calculating survival related variable and univariate analysis,and Cox regression was used for calculating HR and multivariate analysis.Results Results of univariate analysis showed that total bilirubin (P =0.045),prealbumin/total bilirubin ratio (P =0.000) and hepatic encephalopathy (P =0.026) were prognostic factors for patients with liver failure.Results of multivariate Cox regression analysis demonstrated that hepatic encephalopathy (HR =1.218;95％ CI:1.021,1.434;P=0.041) and the prealbumin/total bilirubin ratio (HR =0.712;95％ CI:0.609,0.853;P=0.000) were independent prognostic factors in patients with liver failure.The prognosis of patients with prealbumin/total bilirubin ratio ＞17.2 was significantly better than that of prealbumin/total bilirubin ≤17.2 (P =0.000).Conclusions The serum prealbumin/total bilirubin ratio is an independent prognostic factor for patients with liver failure and it is valuable in prediction of prognosis in patients with liver failure,which is worth further clinical application.关键词
肝衰竭/前白蛋白/总胆红素/预后因素Key words
liver failure/prealbumin/total bilirubin/prognostic factor分类
医药卫生引用本文复制引用
赵紫烟,安雪青,史丽,童国相..血清前白蛋白/总胆红素比值对肝衰竭患者预后的预测价值[J].中国现代医学杂志,2017,27(21):75-78,4.
