中国药房2017，Vol.28Issue(27)：3763-3767,5.DOI:10.6039/j.issn.1001-0408.2017.27.05
非瓣膜性房颤患者华法林用药依从性及其影响因素的调查分析
Investigation and Analysis of Medication Compliance of Patients with Nonvalvular Atrial Fibrillation to Warfarin and Its Influential Factors
摘要
Abstract
OBJECTIVE:To improve medication compliance of patients with nonvalvular atrial fibrillation (NVAF) to warfarin and its influential factors,and to provide reference for guaranteeing the safety and effectiveness of therapy.METHODS:A questionnaire survey was conducted among NVAF patients receiving warfarin anticoagulation in our hospital,MMAS-8 and WRKS were adopted to evaluate medication compliance of patients to warfarin and the understanding of patients to the knowledge of anticoagulation treatment.Related influential factors for medication compliance of patients to warfarin were investigated by x2 test,t test and Logistic multiple regression analysis.RESULTS:Totally 129 questionnaires were sent out,and 112 were effectively received with effective recovery of 86.82％.The mean score of MMAS was (6.54 ± 1.61),and 42.86％ patients had good medication compliance.The mean score of WRKS was (7.95 ± 1.65);that of patients with good medication compliance was (9.31 ± 0.83),and that of patients with poor medication compliance was (6.92 ± 1.34).Single factor analysis showed that there was statistical significance in gender,age,occupation,educational level,the number of compliance,WRKS score between patients with good medication compliance and those with poor medication compliance (P＜0.05).Multivariate Logistic regression analysis showed that WRKS score,gender,educational level and the number of compliance were significantly correlated with medication compliance (P＜0.05).CONCLUSIONS:Poor medication compliance of NVAF patients to warfarin is related to multiple influential factors.The knowledge of warfarin anticoagulation is an important factor.关键词
非瓣膜性房颤/华法林/用药依从性/影响因素Key words
Nonvalvular atrial fibrillation/Warfarin/Medication compliance/Influential factor分类
医药卫生引用本文复制引用
陈文文,党和勤,耿涛,张秀珍,李元民..非瓣膜性房颤患者华法林用药依从性及其影响因素的调查分析[J].中国药房,2017,28(27):3763-3767,5.基金项目
泰山医学院附属医院青年科学基金计划项目(No.2014QN05) （No.2014QN05）
