中国药房2017,Vol.28Issue(27):3785-3787,3.DOI:10.6039/j.issn.1001-0408.2017.27.11
仙灵骨葆胶囊致不良反应185例文献分析
Literature Analysis of 185 Cases of ADR Induced by Xianling Gubao Capsule
杜倩 1王哲 2运乃茹 3黄宇虹 3徐强 3王保和3
作者信息
- 1. 天津中医药大学研究生院,天津300073
- 2. 天津中医药大学中医学院,天津300073
- 3. 天津中医药大学第二附属医院,天津300150
- 折叠
摘要
Abstract
OBJECTIVE:To investigate the regularity and characteristics of adverse drug reactions (ADR) induced by Xianling gubao capsule,and to provide reference for rational drug use in the clinic.METHODS:ADR induced by Xianling gubao capsule were retrieved from CJFD,CBM,Wanfang database,VIP during Jan.2007-Oct.2016.The related information of 185 ADR cases were statistically analyzed.RESULTS:Among 185 patients,primary disease was mainly osteoporosis (63 cases,34.05%).The incidence of ADR induced by drug combination (70.81%) was higher than single drug (29.19%).ADR mostly occurred within 90 d after medication (67.03%).Main clinical manifestation was digestive system damage (82.68%).Most patients (61.62%) did not need treatment,symptomatic treatment or drug withdrawal to relieve ADR symptoms.CONCLUSIONS:The monitoring for ADR induced by Xianling gubao capsule should be strengthened in clinic,especially for ADR of liver fuction,soas to promote rational drug use.关键词
仙灵骨葆胶囊/不良反应/文献分析/合理用药Key words
Xianling gubao capsule/ADR/Literature analysis/Rational drug use分类
医药卫生引用本文复制引用
杜倩,王哲,运乃茹,黄宇虹,徐强,王保和..仙灵骨葆胶囊致不良反应185例文献分析[J].中国药房,2017,28(27):3785-3787,3.