中国药业2017，Vol.26Issue(20)：9-12,4.DOI:10.3969/j.issn.1006-4931.2017.20.003
响应面法优化徐长卿中丹皮酚提取工艺研究
Optimization of Extraction Process of Paeonol in Cynanchum Paniculatum by Response Surface Method
摘要
Abstract
Objective To optimize the extraction process of paeonol in Cynanchum paniculatum by response surface method(RSM). Methods The paeonol was extracted in Cynanchum paniculatum by steam distillation. The extraction process was optimized by RSM,the effect of extraction time (A),ratio of liquid to material (B)and amount of sodium chloride (C)as the independent variable,OY Value (Y)as the dependent variable,the multiple linear equation regression and the quadratic polynomial equation fitting were carried out respectively,and the optimal extraction process was selected and validated. Results The optimal extraction conditions were as follows:immersion time was 3 h,ratio of material to liquid was 1 :15,and sodium chloride was 150 g/kg. Conclusion The optimization process can be used to extract paeonol in Cynanchum paniculatum,the method is simple,stable and feasible.关键词
响应面法/水蒸气蒸馏法/徐长卿/丹皮酚/提取工艺Key words
response surface method/steam distillation/Cynanchum paniculatum/paeonol/extraction process分类
化学化工引用本文复制引用
郭伊霖,宗时宇,浦益琼,徐本亮,王冰..响应面法优化徐长卿中丹皮酚提取工艺研究[J].中国药业,2017,26(20):9-12,4.基金项目
上海市教育委员会预算内科研项目[ 2014YSN28 ]. （）
