摘要
Abstract
Objective To optimize the best extraction process for Radix Salviae miltiorrhizae and Ligusticum chuanxiong. Methods The tanshinoneⅡA,ferulic acid and dry extract yield were taken as the evaluation indexes of ethanol extraction process,the salvianolic acid B and dry extract yield were taken as the evaluation indexes of water extraction process,the optimum extraction process was screened by orthogonal test. Results The optimum extraction process of Radix Salviae Miltiorrhizae and Ligusticum Chuanxiong was adding 8 times amount of 80％ alcohol,refluxing and extracting for 3 times,1. 5 h each time. The residue was adding 8 times amount of water,refluxing and extracting for 3 times,1. 5 h each time,then concentrating the water extraction to ρ=1. 10 ( determined at 60 ℃) ,letting it at room temperature and adding 95％ alcohol to 65％,standing overnight,filtration,recycling ethanol to no alcohol flavor. Conclusion The optimized extraction process of Radix Salviae miltiorrhizae and Ligusticum chuanxiong by orthogonal test is stable and feasible,and the extraction rate of effective ingredients is high,which can provide experimental basis for industrial production.关键词
丹参/川芎/丹参酮ⅡA/丹酚酸B/阿魏酸/提取工艺/正交试验Key words
Salvia miltiorrihiza/Ligusticun chuanxiong/tanshinoneⅡA/salvianolic acid B/phenolic acid/extraction process/orthogonal test分类
化学化工
