中国药业2017，Vol.26Issue(20)：48-50,3.DOI:10.3969/j.issn.1006-4931.2017.20.014
法舒地尔联合α-硫辛酸治疗阳痿可行性及安全性评价
Feasibility and Safety of Fasudil Combined with α-Lipoic Acid for Treating Impotence
王小玲1
作者信息
- 1. 青海省海南藏族自治州人民医院,青海海南 810001
- 折叠
摘要
Abstract
Objective To study the feasibility and safety of fasudil combined with α-lipoic acid for treating impotence. Methods A total of 84 patients with impotence diagnosed for the first time were randomly divided into the control group and the observation group, 42 cases in each group. The control group was given sildenafil orally,50 mg per time,1 d/time for 3 weeks,while the observation group was given 10 μg fasudil + 100 mL 0. 9％ Sodium Chloride Injection combined with 600 mg α-lipoic acid+250 mL 0. 9％Sodium Chloride Injection,ivgtt,1 d/time for 3 weeks. The efficacy and adverse reaction of the two groups were compared. Results Af-ter 3 weeks of treatment,there was no significant difference in the IIEF-5 scores and the hardness of penile erection between the two groups (P > 0. 05),after 3 months and 6 months follow-up,the IIEF-5 score and the hardness of penile erection of the observation group were significantly higher than those of the control group(P < 0. 05). After 6 months follow-up,the total effective rate of the observation group was significantly higher than that of the control group (P < 0. 05),and there was no serious complication in the two groups. Conclusion Fasudil combined with α-lipoic acid for treating impotence has good effect and safety.关键词
法舒地尔/α-硫辛酸/阳痿/可行性/安全性Key words
fasudil/α-lipoic acid/impotence/feasibility/safety分类
医药卫生引用本文复制引用
王小玲..法舒地尔联合α-硫辛酸治疗阳痿可行性及安全性评价[J].中国药业,2017,26(20):48-50,3.
