中国医院用药评价与分析2017,Vol.17Issue(9):1211-1212,1215,3.DOI:10.14009/j.issn.1672-2124.2017.09.022
替米沙坦片联合百令胶囊治疗慢性肾小球肾炎的疗效及对肾功能的影响
Efficacy of Telmisartan Combined with Bailing Capsule in Treatment of Chronic Glomerulonephritis and Its Effect on Renal Function
周英勇 1赵点1
作者信息
- 1. 江西省永修县人民医院内科,江西永修 330304
- 折叠
摘要
Abstract
OBJECTIVE:To probe into the efficacy of telmisartan combined with Bailing capsule in treatment of chronic glomerulonephritis and its effect on patients ' renal function. METHODS: 110 patients with chronic glomerulonephritis were selected and divided into control group and observation group via random number table, with 55 cases in each group. The control group was treated with telmisartan, while the observation group was given telmisartan combined with Bailing capsule. 4 months after treatment, the efficacy, incidence of adverse drug reactions and changes of levels of serum creatinine ( Scr) , blood urea nitrogen ( BUN) , 24 h urine protein quantitation ( UPQ) before and after treatment of two groups were observed. RESULTS:After treatment, levels of Scr, BUN and 24 h UPQ of both groups were significantly lower than those of before treatment, and those of observation group were significantly lower than the control group, with statistically significant difference (P<0. 05);the total effective rate of observation group was 89. 09%(49/55), which was significantly higher than that of the control group (72. 73%,40/55), with statistically significant difference ( P < 0. 05 ) . No severe adverse drug reactions were found in both groups. CONCLUSIONS:The efficacy of telmisartan combined with Bailing capsule in treatment of chronic glomerulonephritis is remarkable, which can significantly improve patients' renal function, with higher safety.关键词
替米沙坦/百令胶囊/慢性肾小球肾炎/肾功能Key words
Telmisartan/Bailing capsule/Chronic glomerulonephritis/Renal function分类
医药卫生引用本文复制引用
周英勇,赵点..替米沙坦片联合百令胶囊治疗慢性肾小球肾炎的疗效及对肾功能的影响[J].中国医院用药评价与分析,2017,17(9):1211-1212,1215,3.