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2013—2016年胆道感染病原菌分布及耐药性分析

薛海玲 孙兰菊 房杰 陈明慧

中国中西医结合外科杂志2017,Vol.23Issue(5):463-467,5.
中国中西医结合外科杂志2017,Vol.23Issue(5):463-467,5.DOI:10.3969/j.issn.1007-6948.2017.05.001

2013—2016年胆道感染病原菌分布及耐药性分析

Distribution and Drug Resistance of Pathogenic Bacteria in Patients of Biliary Tract Infection from 2013 to 2016

薛海玲 1孙兰菊 1房杰 1陈明慧1

作者信息

  • 1. 天津南开医院检验科 天津 300100
  • 折叠

摘要

Abstract

Objective To investigate the distribution and antibiotic resistance of pathogenic bacteria from the patients of biliary tract infection in Tianjin Nankai Hospital from 2013 to 2016 and provide the reference for clinical treatment. Methods The identification and the susceptibility test of the isolated bacteria were per-formed by the automatic VITEK-2 compact system,and the data was collected and analyzed using WHONET 5.6 software. Results The positive rate of bile culture was 55.53%(2631/4738). A total of 4539 bacterial strains were isolated,including 2815 strains (62.02%) of Gram-negative bacilli,1675(36.90%) strains of Gram-positive cocci and 49(1.08%) strains of fungus. The top six bacteria were Escherichia coli (26.06%), Klebsiella pneumonia (11.87%),Enterococcus faecium (10.58%),Enterococcus faecalis (10.22%),Pseudomonas aeruginosa (4.30%) and Enterobacter cloacae(3.90%).Those of Escherichia coli and Klebsiella pneumonia pro-ducing ESBLs were 54.27% and 31.54% respectively. About the two kinds,the rates of resistance to carbapen-ems were 0.76% and 0.93%. About Pseudomonas aeruginosa and Acinetobacter baumannii,the rates of resis-tance to carbapenem were 38.46% and 28.97% respectively,about Enterococcus faecium,the rate of resistance to vancomycin was 0.63%.The detection rates of MRSA and MRCNS were 56.04% and 76.79%. Conclusion The most common pathogens in biliary tract infection were intestinal,the species of resistant pathogenic bacte-ria has increased gradually. The Pseudomonas aeruginosa and Acinetobacter baumannii,carbapenem resistant Escherichia coli and Klebsiella pneumonia,and vancomycin resistant enterococcus (VRE) has appeared.

关键词

胆道感染/胆汁/病原菌/耐药性

Key words

Biliary tract infection/bile/patho-gens/antibiotic resistance

分类

医药卫生

引用本文复制引用

薛海玲,孙兰菊,房杰,陈明慧..2013—2016年胆道感染病原菌分布及耐药性分析[J].中国中西医结合外科杂志,2017,23(5):463-467,5.

中国中西医结合外科杂志

OACSTPCD

1007-6948

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