口腔疾病防治2017，Vol.25Issue(10)：633-637,5.DOI:10.12016/j.issn.2096-1456.2017.10.004
表没食子儿茶素没食子酸酯对乳牙早期釉质龋的再矿化作用
Study on application of natural medicine epigallocatechin gallate for primary enamel caries remineralization
摘要
Abstract
Objective This in vitro study aimed to investigate the remineralization effect of the natural medicine epigallocatechin gallate on artificial enamel caries in primary human teeth. Methods We divided 30 sound primary upper anterior teeth into 3 groups according to a random number table, including experimental group (epigallocatechin gallate group),positive control group(NaF group)and blank control group(artificial saliva group),with 10 teeth in each group.After test in vitro,Micro Hardness Tester was applied to measure hardness of samples before and after demineral-ization.Scanning electron microscopy(SEM)was used to observe the result of primary enamel surface remineralization. Results A significant increase in enamel surface microhardness between the three groups after remineralization (F=1 199.975,P<0.05).The difference between 2 groups was compared with each other among 3 groups.Statistical signifi-cance was found (vs experimental group q=41.986, P<0.05; vs positive control group q=68.174, P<0.05), suggest-ing that both positive control group and experimental group could promote the remineralization of primary enamel, and the effect of epigallocatechin gallate was weaker than NaF(q=26.188,P<0.05).The results from SEM indicated that there was large amount of sediment on the surface of primary enamel surface of incisors in the experimental group and positive control group,while primary enamel surface of incisors in the blank control group was honeycomb and uneven, with less sediment.Conclusion Based on this in vitro study,epigallocatechin gallate can promote the remineralization of demineralized enamel of primary teeth,indicating its potential use as a natural remineralization medicine.关键词
表没食子儿茶素没食子酸酯/乳牙釉质龋/再矿化/显微硬度/扫描电镜Key words
Epigallocatechin Gallate/Primary enamel caries/Remineralization/Microhardness/Scanning electron microscopy分类
医药卫生引用本文复制引用
朱丽德孜·托列别克,梁秋娟,周晶,吴佩玲..表没食子儿茶素没食子酸酯对乳牙早期釉质龋的再矿化作用[J].口腔疾病防治,2017,25(10):633-637,5.基金项目
新疆医科大学创新基金项目(XJC201348) （XJC201348）
