口腔疾病防治2017，Vol.25Issue(10)：638-640,3.DOI:10.12016/j.issn.2096-1456.2017.10.005
透明质酸酶在口腔鳞癌组织中的表达及其临床意义
The analysis of expression of HAase in oral squamous cell carcinoma
摘要
Abstract
Objective To evaluate the expression of HAase in Oral Squamous Cell Caricinoma (OSCC). Methods The distribution and expression of HAase in 21 patients with OSCC and their resecetions with tumor-free margins were examined by immunohistochemistry method.Results HAase were mainly immunostained in tumor tissue.The expres-sion of HAase in oral cancer with nodal metastasis and low pathological grades were higher than that with no nodal me-tastasis and high pathological grades (P<0.05), whereas no difference between the TNM stages (P>0.05). Conclu-sion The Haase levels were high in oral squamous cell carcinoma tissues,and rising in patients with lymph node me-tastasis and poorly differentiated.关键词
口腔/鳞状细胞癌/透明质酸酶/肿瘤/免疫组织化学Key words
Oral/Squamous cell carcinoma/Hyaluronidase/Tumor/Immunohistochemistry分类
医药卫生引用本文复制引用
王敬旭,廖贵清..透明质酸酶在口腔鳞癌组织中的表达及其临床意义[J].口腔疾病防治,2017,25(10):638-640,3.基金项目
国家自然科学基金项目(30572062) （30572062）
