摘要
Abstract
Objective To investigate the short-term efficacy of implant in the treatment of patients with dentition defect caused by chronic periodontitis.Methods 53 patients with mild to moderate chronic periodontitis treated in our hospital from June 2014 to May 2015 were selected as observation group, and 53 patients without periodontal diseases in the same period were selected as control group.The plaque index(PLI), sulcus bleeding index(SBI), periodontal probing depth (PD) and gingival papilla index (PIS) were measured at six months and one year after operation, respectively. Interleukin-6(IL-6), interleukin-8(IL-8), high sensitive C-reactive protein(hs-CRP)and tumor necrosis factor-α(TNF-α)were detected at six months and one year after operation,respectively.At the last follow-up, the survival rate of two groups were calculated.Results One year after operation,5 of the 64 implants in the observation group failed compared with 2 of the 71 implants in the control group.There was no statistical difference in the implant survival rate between the two groups (92.19% vs 97.18%, P=0.191). There was no significant difference in SBI (t=0.936,P=0.351)、PLI (t=0.457, P=0.649)、PIS (t=1.132, P=0.217)、PD (t=0.957, P=0.341) between the two groups at six months after operation. One year after operation, the periodontal index of the observation group was higher than that of the control group SBI (t=5.297, P=0.000)、PLI (t=2.341, P=0.021)、PIS (t=8.218, P=0.000) and PD (t=6.492, P=0.000). The levels of IL-6 (t=6.463,P=0.000)、IL-8 (t=7.202,P=0.000)、hs-CRP (t=4.237,P=0.000) and TNF-α (t=6.194,P=0.000)in the observation group were higher than those in the control group at six months after operation.One year after operation, the level of inflammatory factors in the observation group was higher than that in the control group IL-6(t=12.835,P=0.000)、IL-8(t=13.207,P=0.000)、hs-CRP(t=11.319,P=0.000)and TNF-α (t=8.117,P=0.000).Conclusion Implant as the treatment of patients with dentition defect caused by chronic periodontitis obtained satisfied short-term effect, but its long-term efficacy remains to be further verified.关键词
种植修复/慢性牙周炎/牙列缺损/龈沟液/炎性因子/短期疗效Key words
Implant restoration/Chronic periodontitis/Dentition defect/Inflammatory factor/Gingival sulcus fluid/Short-term effect分类
医药卫生
