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转录因子Nanog在恶性肿瘤发展中的作用

解丽君

临床与病理杂志2017,Vol.37Issue(9):1943-1949,7.
临床与病理杂志2017,Vol.37Issue(9):1943-1949,7.DOI:10.3978/j.issn.2095-6959.2017.09.030

转录因子Nanog在恶性肿瘤发展中的作用

Role of transcriptional factor Nanog in the development of malignant tumor

解丽君1

作者信息

  • 1. 河北省疾病预防控制中心药物研究所,石家庄 050021
  • 折叠

摘要

Abstract

Nanog is a transcription factor that is involved in the self-renewal of embryonic stem cells (ES) and is a critical factor for the maintenance of the undifferentiated state of pluripotent cells. Extensive data in the literature show that the Nanog gene is aberrantly expressed during the development of malignancy in cancer cells. Nanog is specifically involved in the process of carcinogenesis and can be a potential biological and prognostic marker for malignant tumors.

关键词

Nanog/肿瘤干细胞/肿瘤发生

Key words

Nanog/cancer stem cell/carcinogenesis

引用本文复制引用

解丽君..转录因子Nanog在恶性肿瘤发展中的作用[J].临床与病理杂志,2017,37(9):1943-1949,7.

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