临床与病理杂志2017，Vol.37Issue(9)：1960-1964,5.DOI:10.3978/j.issn.2095-6959.2017.09.033
脑死亡动物模型的研究进展
Research progress of animal model of brain death
王建桥 1吕浩同2
作者信息
- 1. 河北省廊坊市人民医院神经内科,河北 廊坊 065000
- 2. 华北理工大学临床医学院,河北 唐山 063000
- 折叠
摘要
Abstract
Brain death models can be used to study the function of transplant donor. Rats, pigs, dogs, rabbits, mice, etc.are often selected for model animals used in brain death studies. Currently, the typical method to establish a brain death model is to increase intracranial pressure suddenly or gradually by inflation of an epidural balloon catheter. The commonly applied models are sudden onset brain death model and gradual onset brain death model.There are still no uniform criteria for the determination of brain death in the model animal. Additionally, some deficiencies of brain death animal models at present are existed yet, and it cannot fully simulate the clinical brain death. The judgment of a successful brain death model is still different from the diagnosis of clinical brain death.关键词
脑死亡/模式动物/突发性脑死亡模型/渐进性脑死亡模型Key words
brain death/model animal/the sudden onset brain death model/the gradual onset brain death model引用本文复制引用
王建桥,吕浩同..脑死亡动物模型的研究进展[J].临床与病理杂志,2017,37(9):1960-1964,5.
