中国实用神经疾病杂志2017，Vol.20Issue(19)：5-9,5.DOI:10.3969/j.issn.1673-5110.2017.19.002
正常人汉字工作记忆功能磁共振脑激活区改变的研究
Study of Chinese character working memory on the brain activation area by using function magnetic resonance in healthy persons
摘要
Abstract
Objective To study the change in the brain activation area underwent Chinese characters working memory by u-sing functional magnetic resonance (fMRI)in healthy persons.Methods Forty healthy persons underwent fMRI while performing Chinese characters working memory task by using block design.Results Frontal lobe,precuneus,cuneus,limbic Lobe,cingulate gyrus were activated in the period of encode,maintain and extraction under Chinese characters working memory,cerebro-spinal and fluid lateral ventricle were activated during the encode and maintain period and were negatively activated in extraction period.In ad-dition to the common activated brain area,all activated brain regions were positively activated during encode period.During the maintain period,precentral gyrus,amygdale and cingulate cortex after 31 (BA)were positively activated and frontal and temporal brain regions and angular gyrus were negatively activated.During the extraction periods,the activated brain regions were caudate nucleus and Broca area.Conclusion In addition to cortical and cortical and subcortical structures,cerebro-spinal and fluid lateral ventricle are also activated under the Chinese characters working memory.关键词
汉字工作记忆/功能磁共振/脑激活区Key words
Chinese characters working memory/fMRI/Brain activation area分类
医药卫生引用本文复制引用
张斌,张杰文,张淑玲,张道培,付胜奇,张红菊..正常人汉字工作记忆功能磁共振脑激活区改变的研究[J].中国实用神经疾病杂志,2017,20(19):5-9,5.基金项目
国家"863"计划资助项目(2012AA011603) （2012AA011603）
河南省科学技术厅科技计划项目(132102610197,1321023100633) （132102610197,1321023100633）
河南省卫生厅重大科技项目(201202023) （201202023）
