摘要
Abstract
Objective To investigate the clinical risk factors of leukoaraiosis.Methods The clinical data of 116 patients with leukoaraiosis who were treated consecutively from January 1,2015 to June 1,2016 were analyzed.LA patients were divided in-to moderate (n =70)and severe (n =46)groups by using the Fazekasz scale of leukoaraiosis,and the clinical data were statistically analyzed.Results 85 cases of leukoaraiosis with hypertension (effective percentage 73.2%),diabetes 15 cases (effective percentage 12.9%),dyslipidemia 76 cases (effective percentage 65.5%),artery atherosclerosis 63 cases (effective percentage 54.3%),and the mean homocysteine level was 21.98 mg/L.Compared with the moderate group,the severe group was older and had lower levels of cholesterol,LDL,apolipoprotein A,and apolipoprotein B (P < 0.05 ),and higher homocysteine levels (P <0.05).Conclusion Age,hypertension,abnormal metabolism of ester,homocysteine and other factors are associated with the oc-currence of LA;in which,age and homocysteine promote the occurrence of LA,and cholesterol,low density lipoprotein and con-tained Lipoproteins A and B were protective factors for LA,and their decrease was associated with a higher Fazekasz scale.关键词
脑白质疏松症/危险因素/脂代谢异常Key words
Leukoaraiosis/Risk factors/Dyslipidemia分类
医药卫生
