临床口腔医学杂志2017，Vol.33Issue(10)：588-591,4.DOI:10.3969/j.issn.1003-1634.2017.10.004
钙离子预处理脱矿牙本质胶原对原花青素交联效果的影响
The effect of calcium pretreatment on the stability of proanthocyanidin-biomodified dentin collagen
摘要
Abstract
Objective:The aim of current study was to investigate the effect of calcium pretreatment on the stability of proanthocyanidin-biomodified dentin collagen. Methods:Phosphoric acid-demineralized dentin beams were divided into two groups:with or without calcium chloride pretreatment. Dentin beams from each groups were divided into three subgroups:dei-onized water group(negative control),glutaradehyde group(positive control),and proanthocyanidin group. The crosslinking effect of proanthocyanidin on dentin beams was evaluated by measuring mass loss, hydroxyproline release, and flexural strength change after biodegradation and evidenced by transmission electron microscopy. Results:Both glutaradehyde and pro-anthocyanidin could lower the collagen degradation(P<0. 05)and improve the flexural strength of dentin beams(P<0. 05). Calcium pretreatment could further enhance the crosslinking effect of proanthocyanidin on dentin collagen. Conclusion:Calci-um pretreatment could improve the crosslinking effect of proanthocyanidin on dentin collagen.关键词
原花青素/交联剂/脱矿/牙本质/酶解Key words
Proanthocyanidin/Crosslinking agents/Demineralization/Dentin/Enzymatic degradation分类
医药卫生引用本文复制引用
吴亚博,杨世缘,毛靖,龚士强..钙离子预处理脱矿牙本质胶原对原花青素交联效果的影响[J].临床口腔医学杂志,2017,33(10):588-591,4.基金项目
国家自然科学基金(81401525) （81401525）
