临床口腔医学杂志2017，Vol.33Issue(10)：620-622,3.DOI:10.3969/j.issn.1003-1634.2017.10.013
唇腭裂患儿中枢听觉神经系统的事件相关电位研究
Event-related potential study of central auditory nervous system of children with cleft lip and/or palate
摘要
Abstract
Objective:To investigate possible functional abnormalities of the central auditory nervous system( CANS) of children with cleft lip and/or palate. Methods:Forty-Six children with cleft lip and/or palate,aged from 3 to 6 years,were divided into 4 groups of cleft lip only,incomplete cleft palate only,unilateral complete cleft palate with cleft lip and bilateral complete cleft palate with cleft lip,and Forty normal infants were as control group. Event-related potential( ERP) P300 were selected as index to observe the function of central auditory nervous system of children in both groups. The data were statisti-cally compared between groups. Results:Compared with the normal controls,the latency of the event-related potential P300 of children with cleft lip and/or palate was significantly prolonged(P<0. 05),and the amplitude was significantly decreased(P<0. 05). No significant group differences were found in 3 groups of incomplete cleft palate only,unilateral complete cleft pal-ate with cleft lip and bilateral complete cleft palate with cleft lip,but significant group differences were found in cleft lip only between 3 groups of cleft palate(P<0. 05),respectively. Conclusion:Children with cleft lip and/or palate may have dys-function of central auditory nervous system. Dysfunction is closely related with the existence of cleft palate,but not with the cleft palate type.关键词
唇腭裂/中枢听觉神经系统/事件相关电位Key words
Cleft lip and palate/Central auditory nervous system/Event-related potential分类
医药卫生引用本文复制引用
束煌,杨峰,丁桂聪,肖宇寒,王骥..唇腭裂患儿中枢听觉神经系统的事件相关电位研究[J].临床口腔医学杂志,2017,33(10):620-622,3.基金项目
深圳市科创委基础研究项目(JCYJ20150403100317070) （JCYJ20150403100317070）
